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Six studies were exclusively performed on male subjects, (Reference Kondori, Ghaleh and Hosseini35,Reference Benlloch, Cuerda Ballester and Drehmer38–Reference Azizbeigi, Stannard and Atashak40,Reference Tabatabaee, Alavian and Ghalichi44,Reference Kuo, Lin, Bernard and Liao52) 4 studies on female subjects, (Reference Naderifar, Gangeh, Mehri and Kazemi33,Reference Nogueira, Nogueira Neto, Klein and Sanjuliani46,Reference Mombaini, Jafarirad, Husain, Haghighizadeh and Padfar47,Reference Mielgo-Ayuso, Barrenechea, Alcorta, Larrarte, Margareto and Labayen54) and others on both genders

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However, in the groups treated with antibiotics or antibiotics plus BBR, the IMT max value did not decline significantly (Group A and Group AB, Fig